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Reagents, Molecular Assay, Gene Anomaly, Mutation, CYP2C9

Definition : Molecular assay reagents intended to identify mutations in the cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9) gene, located at chromosome 10q24, which encodes a member of the cytochrome P450 superfamily of enzymes. P450 cytochrome is involved in the processing of ingested drugs and synthesizing of cholesterol, steroid hormones, and lipids. Mutations at this locus have been identified in patients who have a slower rate of warfarin metabolism. Determination of the patient's CYP2C9 genotype may guide the choice of the initial warfarin dose, potentially reducing the period of time before the standard method of measuring the extrinsic pathway of coagulation (i.e., prothrombin time and/or the international normalized ratio [INR]) stabilizes.

Entry Terms : "CYP2C9 Gene Mutation Detection Reagents" , "Warfarin Dose Determination Reagents"

UMDC code : 26996

   

1-5 of 5 Match(es).

BD Biosciences - European Headquarters

BD Biosciences - European Headquarters

BD Biosciences PharMingen

BD is a medical technology company that serves healthcare institutions, life science researchers, clinical laboratories, industry and the general public. BD manufactures and sells a broad range of medical supplies, devices, laboratory equipment and diagnostic products. BD is headquartered in the United States and has offices in more than 50 countries worldwide.

Idaho Technology Inc

The Company currently holds over 70 patents related to polymerase chain reaction (PCR), including rapid PCR cycling. The Company has used its extensive patent portfolio to successfully market nearly 200 products to the clinical, research and military markets. The Company manufactures and distributes its proprietary diagnostic respiratory panel, FilmArray RP, which operates on its user-friendly FilmArray system, to hospital-based clinical laboratories in the U.S. and E.U.

Promega Corp

Promega Corporation's 2,000 products enable scientists worldwide to advance their research in the life sciences, particularly in genomics, proteomics, and cellular analysis. Our products are also used to support molecular diagnostics and human identification.

Sacace Biotechnologies srl

Sacace Biotechnologies srl

1-5 of 5 Match(es).

 

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