Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, CYP2C9

IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, CYP2C9

Definition : Molecular assay reagents intended to identify mutations in the cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9) gene, located at chromosome 10q24, which encodes a member of the cytochrome P450 superfamily of enzymes. P450 cytochrome is involved in the processing of ingested drugs and synthesizing of cholesterol, steroid hormones, and lipids. Mutations at this locus have been identified in patients who have a slower rate of warfarin metabolism. Determination of the patient's CYP2C9 genotype may guide the choice of the initial warfarin dose, potentially reducing the period of time before the standard method of measuring the extrinsic pathway of coagulation (i.e., prothrombin time and/or the international normalized ratio [INR]) stabilizes.

Entry Terms : "CYP2C9 Gene Mutation Detection Reagents" , "Warfarin Dose Determination Reagents" , "Reagents, Molecular Assay, Gene Anomaly, Mutation, CYP2C9"

UMDC code : 26996

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Assurex Health Inc

Company Type: Parent

BD

Company Type: Parent

BD is a medical technology company that serves healthcare institutions, life science researchers, clinical laboratories, industry and the general public.

Mayo Medical Laboratories

Company Type: Parent

Promega Corp

Company Type: Parent

Promega Corporation's 2,000 products enable scientists worldwide to advance their research in the life sciences, particularly in genomics, proteomics, and cellular analysis. Our products are also used to support molecular diagnostics and human identification.

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