IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Trinucleotide Repeats, CAG, HTT Gene
Definition : Molecular assay reagents intended to identify CAG repeats in the Huntingtin (HTT) gene, located at chromosome 4p16.3. Normal alleles have from 10 to 35 CAG trinucleotide repeats. A variation from the expected number of normal CAG trinucleotide repeat copies may produce altered DNA and improper gene functioning, resulting in full mutation. Alleles with 36 to more than 120 CAG trinucleotide repeats have been associated with Huntingdon's disease.
Entry Terms : "Huntington Chorea Gene Mutation Reagents" , "Huntington Disease Gene Mutation Reagents" , "HTT Gene Mutation Detection Reagents, CAG Trinucleotide Repeats" , "Reagents, Molecular Assay, Gene Anomaly, Trinucleotide Repeats, CAG, HTT Gene"
UMDC code : 25027