IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Trinucleotide Repeats, CAG, ATXN2 Gene
Definition : Molecular assay reagents intended to identify CAG repeats in the ataxin 2 (ATXN2) gene, located at chromosome 12q24.1. A variation from the expected number of normal CAG trinucleotide repeat copies may produce altered DNA and improper gene functioning, resulting in full mutation. Normal alleles have 31 or fewer CAG trinucleotide repeats. Alleles with more than 32 CAG trinucleotide repeats have been associated with spinocerebellar ataxia type 2 (SCA2).
Entry Terms : "Olivopontocerebellar Atrophy Type 2 Gene Mutation Reagents" , "Spinocerebellar Ataxia Type 2 (SCA2) Gene Mutation Reagents" , "Ataxia Gene Mutation Reagents" , "ATXN2 Gene Mutation Detection Reagents, CAG Trinucleotide Repeats" , "Reagents, Molecular Assay, Gene Anomaly, Trinucleotide Repeats, CAG, ATXN2 Gene"
UMDC code : 25024