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Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, MXI1

IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, MXI1

Definition : Molecular assay reagents intended to identify mutations in the MAX interacting protein 1 (MXI1) gene, located at chromosome 10q24-25, which encodes for a protein that is a transcriptional repressor, thought to negatively regulate Myc function. This gene is a potential tumor suppressor. Mutations at this locus have been identified in patients with neurofibrosarcoma and susceptibility to prostate cancer.

Entry Terms : "Schwannoma Gene Mutation Reagents" , "Neurofibrosarcoma Gene Mutation Reagents" , "MXI1 Gene Mutation Detection Reagents" , "Reagents, Molecular Assay, Gene Anomaly, Mutation, MXI1"

UMDC code : 24631

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