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Reagents, Molecular Assay, Gene Anomaly, Mutation, CDH1

Definition : Molecular assay reagents intended to identify mutations in the cadherin 1, type 1, E-cadherin (epithelial) (CDH1) gene, located at chromosome 16q22.1, which encodes for a calcium-dependent cell-cell adhesion glycoprotein. Mutations at this locus have been identified in patients with early-onset gastric, breast, colorectal, thyroid, and ovarian cancer.

Entry Terms : "Signet Ring Carcinoma Gene Mutation Detection Reagents" , "Hereditary Diffuse Gastric Cancer (HDGC) Gene Mutation Detection Reagents" , "CDH1 Gene Mutation Detection Reagents"

UMDC code : 24333

   

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