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Reagents, Molecular Assay, Gene Anomaly, Mutation, APOE

Definition : Molecular assay reagents intended to identify mutations in the apolipoprotein E (APOE) gene, located at chromosome 19q13.2, which encodes for apolipoprotein E, a major component of very-low-density lipoproteins (VLDL), key to removing excess cholesterol from the blood and transfering it to the liver for processing. Mutations at this locus have been identified in patients with cardiovascular disorders and especially with hyperlipoproteinemia type 3 (also known as familial dysbetalipoproteinemia) and to late-onset Alzheimer's disease type 3.

Entry Terms : "Alzheimer Disease Type 3 Gene Mutation Detection Reagents" , "Early-onset Coronary Heart Disease Gene Mutation Detection Reagents" , "Aggressive Multiple Sclerosis Gene Mutation Detection Reagents" , "Familial Hyperlipoproteinemia Type III Gene Mutation Detection Reagents" , "Familial Dysbetalipoproteinemia Gene Mutation Detection Reagents" , "APOE Gene Mutation Detection Reagents" , "Alzheimer Disease Diagnostic Reagents"

UMDC code : 24290

   

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