Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Chromosome Anomaly, Translocation, t(12;21)(p12;q22) ETV6/RUNX1

IVD Test Reagent/Kits, Molecular Assay, Chromosome Anomaly, Translocation, t(12;21)(p12;q22) ETV6/RUNX1

Definition : Molecular assay reagents intended to identify exchanges (i.e., translocations) between chromosome 12, band p12 and chromosome 21 band q22; usually involving genes ETV6 and AML1 (acute myeloid leukemia 1 gene) respectively. This translocation is one of the most frequent translocations found in B cell acute lymphoblastic leukemia of children and is associated with a long disease-free survival. Its detection may be used as a tumor marker.

Entry Terms : "Acute Lymphoblastic Leukemia Diagnostic Reagents" , "Leukemia Diagnostic Reagents" , "Chromosome Translocation t(12;21)(p12;q22) DEtection Reagents" , "IVD Test Reagent/Kits, Molecular Assay, Chromosome Anomaly, Translocation, t(12;21)(p12;q22)" , "Reagents, Molecular Assay, Chromosome Anomaly, Translocation, t(12;21)(p12;q22)"

UMDC code : 24062

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Empire Genomics

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Mayo Medical Laboratories

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