IVD Test Reagent/Kits, Molecular Assay, Chromosome Anomaly, Translocation, t(8;22)(q24;q11)
Definition : Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosome 8 band q24 and chromosome 22 band q11, usually involving gene C-MYC on chromosome 8 juxtaposed with gene IGL at the immunoglobulin locus on chromosome 22. This translocation is characteristic of most patients with Burkitt's cell leukemia or Burkitt's lymphoma; other translocations involving the MYC locus and associated with Burkitt's lymphoma include t(8:14)(q24:q32) and t(2;8)(p12;q24). Its detection may be used as a tumor marker.
Entry Terms : "Chromosome Translocation t(8;22)(q24;q11) Detection Reagents" , "Reagents, Molecular Assay, Chromosome Anomaly, Translocation, t(8;22)(q24;q11)"
UMDC code : 24050