Protein/Peptide Processors, Synthesis
Definition : Protein/peptide processors designed for automated synthesis of peptides and/or proteins from protected amino acids. These instruments typically perform a three-step cyclic process that includes removing the protecting group from the amino group at the end of the peptide chain (deprotection), converting the next amino acid to be added to an active ester (activation), and forming an amide bond between the active ester and the deprotected alpha-amino group (coupling). When synthesis is complete, the synthesized peptide is removed. These processors frequently perform synthesis in reagent bottles attached to the instrument and peptide synthesis columns that include solid resins; the processors also include computerized systems with appropriate software.
Entry Terms : "Synthesizers, Peptide" , "Protein Synthesizers" , "Peptide Synthesizers"
UMDC code : 20815