Reagents, Immunoassay, Autoimmune, Neurologic, Antiganglioside Antibody, GM2
Definition : Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine antibodies to the ganglioside GM2 (i.e., anti-GM2 antibodies). These antibodies are associated to neuropathies, such as Guillain-Barre syndrome (GBS); they are frequently present in the serum from GBS patients with an antecedent infection with cytomegalovirus; antibodies to a rare form (i.e., variant B1) of GM2 gangliosides are associated with neurodegenerative disorders such as speech, gait, and seizures in children.
Entry Terms : "GM2 Anti-Ganglioside Antibody Determination Reagents" , "Anti-Ganglioside Antibody Determination Reagents, GM2"
UMDC code : 20087