Home > Specialties > Reagents, Immunoassay, Toxicology, Antidepressant

Reagents, Immunoassay, Toxicology, Antidepressant

Definition : Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine one or more of a group of drugs that stimulates the mood of a depressed patient (i.e., antidepressants). The most frequently administered antidepressants contain three fused rings in their chemical structure (i.e., tricyclic antidepressants). They include amitryptiline, desipramine, doxepin, imipramine, and nortriptyline. Some tetracyclic drugs are also used as antidepressants. Reagents used to determine antidepressant concentration in blood differentiate therapeutic levels (typically very low) from toxic levels due to overdose. Tricyclic antidepressant concentration in serum is directly related to therapeutic response, with the exception of nortriptyline which has a specific therapeutic window (typically 50 to 150 nanograms/milliliter). The metabolism of tricyclic antidepressants, especially their hydroxylation, results in the formation of active metabolites, which contribute to both the therapeutic and the adverse effects of these compounds.

Entry Terms : "Antidepressant Determination Reagents"

UMDC code : 20052

   

1-16 of 16 Match(es).

Bio-Rad (France)

Bio-Rad (France)

Bio-Rad Hungary Kft

Bio-Rad Hungary Kft

Bio-Rad Laboratories (Singapore) Pte Ltd

Bio-Rad Laboratories (Singapore) Pte Ltd

Bio-Rad Laboratories AG

Bio-Rad Laboratories AG

Bio-Rad Laboratories bv

Bio-Rad Laboratories bv

Bio-Rad Laboratories Ges mbH

Bio-Rad Laboratories Ges mbH

Bio-Rad Laboratories GmbH

Bio-Rad Laboratories GmbH

Bio-Rad Laboratories Inc

Bio-Rad Laboratories continues to play a leading role in the advancement of scientific discovery by offering a broad range of innovative tools and services to the life science research and clinical diagnostics markets. Founded in 1952, Bio-Rad has a global team of more than 7,000 employees and serves more than 100,000 research and industry customers worldwide through the company's global network of operations.

Bio-Rad Laboratories Inc

Bio-Rad Laboratories continues to play a leading role in the advancement of scientific discovery by offering a broad range of innovative tools and services to the life science research and clinical diagnostics markets. Founded in 1952, Bio-Rad has a global team of more than 7,000 employees and serves more than 100,000 research and industry customers worldwide through the company's global network of operations.

Bio-Rad Laboratories Ltd

Bio-Rad Laboratories Ltd

Bio-Rad Laboratories Ltd (UK)

Bio-Rad Laboratories Ltd (UK)

Bio-Rad Laboratories Pty Ltd

Bio-Rad Laboratories Pty Ltd

Bio-Rad Laboratories srl

Bio-Rad Laboratories srl

Bio-Rad Pacific Ltd

Bio-Rad Pacific Ltd

Bio-Rad SA-NV (Belgium)

Bio-Rad SA-NV (Belgium)

Bio-Rad Thailand

Bio-Rad Thailand

1-16 of 16 Match(es).

 

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