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Reagents, Immunoassay, Gastrointestinal Hormone, Gastrin

Definition : Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum) to determine gastrin, a generic name for a group of polypeptide hormones secreted by the endocrine glands of the gastrointestinal tract and also by the brain. Gastrin stimulates gastric acid and pepsinogen secretion; it exists at least in three molecular forms: big gastrin (G-34), little gastrin (G-17), and mini gastrin (G-14). All of these circulate in either sulfated or nonsulfated forms. Immunoassays for gastrin are typically specific for the C-terminal of gastrin; they react equally with all gastrin molecules either in sulfated or nonsulfated forms. Highly increased levels of gastrin in serum are associated with pancreatic and duodenal endocrine tumors (i.e., gastrinomas). High levels are found in patients with common peptic ulcers and other diseases, such as pernicious anemia, chronic renal failure, and rheumatoid arthritis.

Entry Terms : "Hormone Determination Reagents, Gastrointestinal" , "Gastrin Determination Reagents"

UMDC code : 19929


1-3 of 3 Match(es).

ALPCO Diagnostics

ALPCO distributed one product in the United States. Within a decade of its founding, ALPCO partnered with more than 40 manufactures and grew its distribution network throughout North America. To further meet the needs of its customers, ALPCO expanded in 2004 with the advent of its Research and Development Division. Within three years, ALPCO launched its first line of organically developed enzyme-linked immunosorbent assay (ELISA) kits for insulin. Since then, ALPCO has solidified its place in the domestic and international markets not only as a distributor, but also as a developer and manufacturer of immunoassays.

Biomol GmbH

Biomol GmbH

Ventana Medical Systems Inc

Ventana Medical Systems, Inc., was launched in 1987 by a professor and practicing pathologist, Dr. Thomas Grogan. Ventana Medical Systems, Inc., a member of the Roche Group, is a world leader and innovator of tissue-based diagnostic solutions for patients worldwide.

1-3 of 3 Match(es).


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