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Reagents, Hematology, Coagulation, Thrombophilia Marker, Activated Protein C Resistance

Definition : Hematology reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (typically plasma) to determine the resistance to activated protein C (APC), usually defined as a low normalized sensitivity APC ratio (e.g., lower than 0.84 in functional testing). The most frequent cause by far of activated protein C resistance (APCR) is the presence of a mutated coagulation factor V (known as factor V Leiden) that is resistant to degradation by activated protein C. APCR is a major risk factor for venous thrombosis and the most common known genetic cause of thrombophilia; APCR may also occur in some diseases (e.g., cancer, diabetes, AIDS) and temporarily during pregnancy.

Entry Terms : "Protein C (Activated) Resistance (APC Resistance) Determination Reagents" , "APC Resistance (Activated Protein C Resistance) Determination Reagents" , "Activated Protein C Resistance Determination Reagents"

UMDC code : 19749

   

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DiaPharma Group Inc

DiaPharma Group, Inc. in West Chester, Ohio sells hemostasis, thrombosis, and apoptosis products in the diagnostic and research fields, and provides strong technical competence and experience to ensure customer expectations will be met or exceeded.

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