Reagents, Molecular Assay, Gene Anomaly, Mutation, MYC
Definition : Molecular assay reagents intended to identify mutations in the v-myc myelocytomatosis viral oncogene homologue (MYC, also known as c-Myc) gene, located at chromosome 8q24, which encodes for a multifunctional, nuclear phosphoprotein that is involved in cell cycle progression, apoptosis, and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations at this locus have been identified in patients with hematopoietic tumors, leukemias, and lymphomas, including Burkitt's lymphoma.
Entry Terms : "Genetic Rearrangement Gene Mutation Reagents" , "Lymphoma Gene Mutation Reagents" , "Burkitt's Lymphoma Gene Mutation Reagents" , "Solid Tumor Cancer Gene Mutation Reagents" , "Reagents, Molecular Assay, Tumor Marker, Gene Mutation, c-myc" , "MYC Gene Mutation Detection Reagents" , "c-myc Proto-Oncogene Mutation Determination Reagents"
UMDC code : 19623