Reagents, Molecular Assay, Gene Anomaly, Mutation, NRAS
Definition : Molecular assay reagents intended to identify mutations in the neuroblastoma RAS viral (v-ras) oncogene homologue (NRAS) gene, located at chromosome 1p13.2, which encodes for a membrane-linked protein that moves between the Golgi apparatus and the plasma membrane. The protein is a small GTPase. Mutations at this locus have been identified in patients with juvenile myleomonocytic leukemia (JMML), colorectal cancer, thyroid cancer, and follicular cancer.
Entry Terms : "Leukemia Gene Mutation Reagents" , "Primary Plasma Cell Leukemia Gene Mutation Reagents" , "Neuroblastoma Gene Mutation Reagents" , "Myeloma Gene Mutation Reagents" , "Multiple Myeloma Gene Mutation Reagents" , "Reagents, Molecular Assay, Tumor Marker, Gene Mutation, N-ras" , "NRAS Gene Mutation Detection Reagents" , "N-ras Oncogene Determination Reagents"
UMDC code : 19620