Reagents, Molecular Assay, Gene Anomaly, Mutation, p53
Definition : Molecular assay reagents intended to identify mutations in the tumor protein p53 (TP53) gene, located at chromosome 17p13.1, that encodes for a protein that acts as a tumor suppressor and induces cellular apoptosis. This inherited genetic mutation has been identified in patients with many types of cancers
Entry Terms : "Cancer Predisposition Syndrome Gene Mutation Reagents" , "Li-Fraumeni Syndrome (LFS) Gene Mutation Reagents" , "Reagents, Molecular Assay, Tumor Marker, Gene Mutation, p53" , "p53 Gene Mutation Detection Reagents" , "p53 Supressor Gene Determination Reagents"
UMDC code : 19618