Reagents, Molecular Assay, Chromosome Anomaly, Translocation, t(15;17)
Definition : Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosomes 15 and 17. The detection of these translocations (e.g., a fusion gene from the PML gene from chromosome 15 and the retinoic acid receptor alpha gene from chromosome 17) may be used as a tumor marker. The translocation is associated with acute promyelocytic leukemia and found in a subset of patients with multiple myeloma.
Entry Terms : "Acute Promyelocytic Leukemia Diagnostic Reagents" , "Leukemia Diagnostic Reagents" , "Reagents, Molecular Assay, Tumor Marker, Chromosome, Translocation, t(15;17)" , "Chromosome Translocation t(15;17) Detection Reagents" , "t(15,17) Chromosome Translocation Determination Reagents" , "Chromosome Translocation Determination Reagents, t(15,17)"
UMDC code : 19269