Reagents, Molecular Assay, Chromosome Anomaly, Translocation, t(14;18)
Definition : Molecular assay reagents intended for use in identifying stable and irreversible exchanges (i.e., translocations) between chromosomes 14 and 18, usually involving the exchange of the BCL2 gene with the joining region of the immunoglobin heavy chain of chromosome 14. The detection of these translocations may be used as a tumor marker. The translocation is present in most patients with follicular lymphomas and in some patients with acute lymphoblastic leukemia.
Entry Terms : "Large Cell Lymphoma Diagnostic Reagents" , "Follicular Lymphoma Diagnostic Reagents" , "Lymphoma Diagnostic Reagents" , "Reagents, Molecular Assay, Tumor Marker, Chromosome, Translocation, t(14;18)" , "Chromosome Translocation t(14;18) Detection Reagents" , "t(14,18) Chromosome Translocation Determination Reagents" , "Chromosome Translocation Determination Reagents, t(14,18)"
UMDC code : 19267